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‘Every app is a dating app’: technology blamed for rise in HIV rates in Pakistan

ShareCompartir Rabies virions are bullet-shaped with nm spike-like glycoprotein peplomers covering the surface. The ribonucleoprotein is composed of RNA encased in nucleoprotein – , phosphorylated or phosphoprotein -Illistration of virus, and polymerase -virus. Rabies virus belongs to the order Mononegavirales, viruses with a nonsegmented, negative-stranded RNA genomes.

Structure Rhabdoviruses are approximately nm long and 75 nm wide.

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S7 and Table 1. Earlier estimates of mutation rates of the NP gene suggested that human H1N1 and classic swine influenza viruses emerged from the avian source around or However, our results suggest that the same NP gene lineage has been circulating in human influenza A viruses since the 19th century, consistent with the report by Gammelin et al. More likely, it was generated by reassortment between previously circulating swine and human strains and introduced avian viruses over a period of years.

It therefore appears that at least 3 reassortant H1N1 variants co-circulated: This evidence may be relevant to the current emergence and potential pandemicity of swine-derived H1N1 viruses in humans 1. The mean TMRCA estimates of the introduced genes of the H2N2 pandemic suggest that the introduction of these 3 genes into human populations occurred 2 to 6 years before the pandemic. This observation is consistent with the phylogenies of the shared genes, with the exception of the NS gene, in which late H2N2 and early H3N2 do not form separate monophyletic lineages e.

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Find articles by Igor V. Received Dec 8; Accepted Feb This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license http: This article has been cited by other articles in PMC.

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Share via Email This article is over 11 months old At Abpara market in Islamabad, stalls offer services loading media files on to mobile phones. Mobile apps and social media have opened new avenues for social encounters in the conservative south Asian country. For gay men and male sex workers in particular, smartphones provide a degree of sexual liberation, a way of connecting with partners away from the streets. Yet many remain unaware of the risks of HIV, allowing the spread of the virus to accelerate.

HIV rates have jumped dramatically in Pakistan over the past 10 years, from 8, people living with HIV in to nearly 46, in — a Social stigma surrounding homosexuality means actual numbers are likely to be much higher. In other developing countries, apps have made it easier to detect the virus and access treatment. But in Pakistan, public debate about HIV is choked by stigma, homosexuality is taboo and, as a result, information on sexually transmitted diseases is severely limited.

Yasir, 41, who wears his hair long and full, his eyes painted with mascara, started as a sex worker seven years ago to support his 10 family members.

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much higher for black and Hispanic women than for white, Asian and Pacific Islander, or American Indian and Alaska Native women. The rates for black women are higher than the rates for all men except black men. (CDC, ) the virus.” 4 HIV Risk for Lesbians, Bisexuals .

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CDV molecular epidemiology in South America is investigated. Abstract Canine distemper virus CDV is a highly contagious pathogen for domestic dogs and several wild carnivore species. In Brazil, natural infection of CDV in dogs is very high due to the large non-vaccinated dog population, a scenario that calls for new studies on the molecular epidemiology.

This study investigates the phylodynamics and amino-acid signatures of CDV epidemic in South America by analyzing a large dataset compiled from publicly available sequences and also by collecting new samples from Brazil. Phylogenetic analysis of the new and publicly available sequences revealed that Brazilian sequences mainly clustered in South America 1 SA1 clade, which has its origin estimated to the late ‘s. The reconstruction of the demographic history in SA1 clade showed an epidemic expanding until the recent years, doubling in size every nine years.

SA1 clade epidemic distinguished from the world CDV epidemic by the emergence of the R Q strain, a very rare and potentially detrimental substitution in the viral genome. The R Q substitution was estimated to have happened in one single evolutionary step in the epidemic history in SA1 clade, emerging shortly after introduction to the continent.

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